Candidate ionotropic taste receptors in the Drosophila larva.

Stewart S, Koh TW, Ghosh AC, Carlson JR.

Department of Molecular, Cellular, and Developmental Biology, Yale University, New Haven, CT 06511.

Proc Natl Acad Sci U S A. 2015 Apr 7;112(14):4195-201. doi: 10.1073/pnas.1503292112. Epub 2015 Mar 30.

A newly-characterized clade of chemosensory receptors is expressed in insect larvae. Understanding more about larval feeding behavior is the first step in protecting important food crops from insect fouling.

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The Drosophila IR20a clade of ionotropic receptors are candidate taste and pheromone receptors.

Koh TW, He Z, Gorur-Shandilya S, Menuz K, Larter NK, Stewart S, Carlson JR.

Department of Molecular, Cellular and Developmental Biology, Yale University, New Haven, CT 06520, USA.

Neuron. 2014 Aug 20;83(4):850-65. doi: 10.1016/j.neuron.2014.07.012. Epub 2014 Aug 7.

A newly characterized clade of chemosensory receptors responds to tastes and pheromones. This work helps us understand more about the behavioral motivations of insects that feed on important food crops--and potentially humans.

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A second-site noncomplementation screen for modifiers of Rho1 signaling during imaginal disc morphogenesis in Drosophila.

Patch K, Stewart SR, Welch A, Ward RE.

Department of Molecular Biosciences, University of Kansas, Lawrence, Kansas, USA.

PLoS One. 2009 Oct 23;4(10):e7574. doi: 10.1371/journal.pone.0007574.

This was a genome-wide screen for genes that interact with Rho1, a gene that drives cancer cell metastasis. Understanding more about its genetic partners may help us prevent cancer progression and tissue infiltration.

Thumbnail Copyright Patch et al.

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